Reported August 2010

ABOUT ALLERGIES: Every year, when spring rolls around, millions of Americans start sneezing and coughing. The culprit is allergies. An allergy is simply a negative reaction to a substance that enters the body that is not toxic in itself. Yet for some reason, it triggers the body’s immune system to go into overdrive, causing a bad reaction in the body. Just about anything can be an allergen: dust mites, pollen, cats, dogs, wasps or bees, milk, eggs, peanuts, and fruits are the most common. Normally, the immune system’s response is the body's defense against invading bacteria and viruses. It senses potential invaders and attacks them by producing antibodies. But during an allergic reaction, a person's immune system mistakes a common allergen as harmful. So it produces antibodies to attack the allergen, and this triggers other cells to release chemicals called histamines, causing allergic symptoms.

ALLERGIC RESPONSE: The most common symptoms of an allergic reaction include sneezing, swelling, itchy eyes, sinus pain, a runny nose, rashes or hives, coughing, and vomiting. In extreme cases, an allergen can cause difficulty in breathing. This is called an anaphylactic reaction, and a severe attack can be fatal if not treated quickly. More than 29,000 people in the U.S. end up in the emergency room every year because of anaphylactic shock. If you have a bad reaction to any food or additive that involves the immune system, you have a food allergy. But the majority of toxic reactions to food are due to food sensitivities, which do not involve the immune system. A food may just contain a molecule that your body has trouble digesting. The most common food sensitivity is lactose intolerance -- the inability to digest the lactose molecules found in cow's milk -- and it affects up to 10 percent of adults.

The American Association of Pharmaceutical Scientists contributed to the information contained in the TV portion of this report.

If you would like more information, please contact:

David Golden, MD
Allergist and Immunologist Johns Hopkins Medical Center
dgolden1@jhmi.edu

American Association of Pharmaceutical Scientists
Joseph Catapano
Communication Specialist
(703) 248-4772
http://www.aapspharmaceutica.com
catapanoj@aaps.org