Why Gaucher Patients Develop Parkinson's Disease
(Ivanhoe Newswire) -- Researchers have found that the process of removing unwanted cellular material may hold the key to links between Gaucher disease and Parkinson's disease.
The study showed that the removal of defective mitochondrial material is an important process in maintaining cellular health. It was found that the neurodegeneration common in Gaucher disease stems from a defect in this process. The resulting build up of toxic proteins can explain the neurodegeneration common in Parkinson's disease later in life.
"The findings may help to explain the increased risk of Parkinson's disease amongst people carrying Gaucher's gene defects," Dr. Michael Duchen, senior author at University College London in the United Kingdom, was quoted as saying.
For more information, contact: Mary Beth O'Leary, firstname.lastname@example.org
SOURCE: Cell Metabolism, May 2013
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